Perilac is used for the short-term management (up to 5 days) of moderately severe acute pain that requires analgesia at the opioid level. It is not intended for mild or chronic pain.
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Ketorolac works by inhibiting prostaglandin synthesis, blocking the cyclooxygenase (COX) enzyme, and thereby reducing pain, inflammation, and fever.
Adults:
IV: 30 mg single dose or every 6 hours (max 120 mg/day)
IM: 60 mg single dose or 30 mg every 6 hours (max 120 mg/day)
Oral: 20 mg once after IV/IM therapy, then 10 mg every 4–6 hours (max 40 mg/day)
⏱ Treatment duration must not exceed 5 days.
Elderly or renal-impaired patients:
IV/IM: 15 mg single dose or every 6 hours (max 60 mg/day)
Oral: 10 mg once after IV/IM therapy, then 10 mg every 4–6 hours (max 40 mg/day)
Children (2–16 years):
0.5 mg/kg IV/IM every 6 hours (max 15 mg/dose; duration ≤ 5 days)
Very common (>10%): Headache, nausea, stomach pain, dyspepsia
Common (1–10%): Drowsiness, dizziness, diarrhea, edema, rash, hypertension
Rare (<1%): GI bleeding, allergic reactions, blurred vision, liver dysfunction
💀 Potentially fatal: Severe anaphylaxis, skin reactions, heart attack, stroke, or GI bleeding
⚠️ Use with caution in elderly patients, those with liver disease, heart failure, or mild renal impairment.
Monitor renal function during prolonged use.
Category C (D in 3rd trimester) — may cause premature closure of the fetal ductus arteriosus.
❌ Hypersensitivity to NSAIDs or aspirin
❌ Asthma, nasal polyps, or bronchospasm
❌ Peptic ulcer, GI bleeding, renal impairment, or coagulation disorders
❌ Pregnancy (especially 3rd trimester) or lactation
❌ Perioperative use in high bleeding risk or dehydration
Keep in a dry place away from light and heat. Keep out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.